吳瑞璋 副教授

授課科目:
質能均衡 / 製藥工程概論 / 數據整理與報告/高等生化與應用 / 人生哲學
辦公室:
工222
實驗室:
生化實驗室
E-mail:
ray_j_wu@cycu.edu.tw
電 話:
03-265-4141

現職

    中原大學 副教授

學歷

    美國德拉瓦大學化學工程學系 博士
    台灣大學化工學士

經歷

    美國DuPont合約研究工程師(5年)
    美國Orchid BioSciences資深研究工程師(2年)
    竹科華聯生物科技研發經理(1年)

研究專長

    薄膜試條、生物晶片

研究領域

    生物感測

著作

    1. Jui-Chuang Wu*;Yin-Huan Chuang; Yu-Chun Wei; Chia-Chi Hsieh; Yuan-Hung Pong; Yenn-Rong Su; Vincent F.-S. Tsai; Guang-Jer Wu* , “Validating METCAM/MUC18 as a Novel Biomarker to Predict the Malignant Potential of Prostate Cancer at an Early Stage by Using a Modified Gold Nanoparticles-Based Lateral Flow Immunoassay” , 2021 , diagnostics; https://doi.org/10.3390/diagnostics11030443 , vol.11 , p.1-18. (SCI期刊)
    2. Yuan-Hung Pong; Yann-Rong Su; Hsing-Wen Lo; Chung-Kun Ho; Chia-Chi Hsieh; Ching-Tung Chu; Yui Whei Chen-Yang; Vincent F.S. Tsai; Jui-Chuang Wu*; Guang-Jer Wu* , “METCAM/MUC18 is a new early diagnostic biomarker for the malignant potential of prostate cancer: Validation with Western blot method, enzyme-linked immunosorbent assay and lateral flow immunoassay” , 2020 , Cancer Biomarkers , vol.27 , p.377-387. (SCI期刊)
    3. Jui-Chuang Wu; Shih-En Jha; Hsun-Yu Huang; Guan-Ting Lin , “DETECTION OF AUTOIMMUNE DISEASEGENES ON MEMBRANE BASED LATERAL FLOW STRIPS” , 2019 , International Journal of Latest Trends in Engineering and Technology , vol.14 , p.34-40.
    4. Jui-Chuang Wu* ; Yu-Shiun Huang , “Rapid Detection of Gene HLA-A3101 on Membrane Based Lateral-Flow Strips” , 2018 , International Journal of Bioscience, Biochemistry and Bioinformatics , vol.8 , p.218-225. (ProQuest.期刊)(Electronic Journals Library, Chemical Abstracts Services (CAS)期刊)(Google Scholar期刊)
    5. Jui-Chuang Wu*; Chih-Hung Chen; Ga-Wei Fu; and Huang-Chin Yang , “Electrophoresis-enhanced detection of deoxyribonucleic acids on a membrane-based lateral flow strip using Avian Influenza H5 genetic sequence as the model” , 2014 , Sensors , vol.14 , p.4399-4415. (SCI期刊)
    6. 吳瑞璋;傅佳瑋;張雅茹 , “矽凝膠三維生物感測器” , 2013 , 化工技術 , vol.244 , p.83-97.
    7. Jui-Chuang Wu; Yai-Hsin Hsu; Dan-Ping Cheng; Ya-Yuen Cheng , “Detection of Deoxyribonucleic Acids on A Membrane Strip” , 2013 , International Journal of Bioscience, Biochemistry and Bioinformatics, , vol.3 , p.243-245.
    8. Jui Chuang Wu; Dan Kai Yang; Yane Shu Lin; Jun Yi Chen , “Investigation of Hybridization Efficiency of a Sequence-Orientated Coaxial DNA Probe Microarryed on Biochips Using Atomic Force Microscope” , 2013 , Applied Mechanics and Materials , vol.315 , p.284-287. (EI期刊)
    9. Jiang, Kai Ren; Huang, Jie-Len; Chen, Chia-Chun; Su, Hung-Ju; Wu, Jui-Chuang* , “ Effect of co-axially hybridized gene targets on hybridization efficiency of microarrayed DNA probes ” , 2011 , Journal of the Taiwan Institute of Chemical Engineers , vol.42 , p.5-12. (SCI期刊)
    10. 吳瑞璋*;鄭丹蘋;張雅茹 , “側向流薄膜試條於生物感測之應用” , 2011 , 工程 , vol.84 , p.72-81.
    11. Yen Kuang Li; Yun-Chu Chen; Kai-Jen Jiang; Jui-Chuang Wu*; Yui Whei Chen-Yang* , “Three-Dimensional Arrayed Amino Aerogel Biochips for Molecular Recognition of Antigens” , 2011 , Biomaterials , vol.32 , p.7347-7354. (SCI期刊)
    12. 林彥旭; 邱繼樂; 吳瑞璋* , “原子力顯微鏡與生物晶片上之應用” , 2011 , 化工 , vol.58 , p.53-63.
    13. Yen Kuang Li; Den-Kai Yang; Yun-Chu Chen; Hung-Ju Su; Jui-Chuang Wu*; Yui Whei Chen-Yang* , “A Novel Three-Dimensional Aerogel Biochip for Molecular Recognition of Nucleotide Acids” , 2010 , Acta Biomaterialia, , vol.0 , p.1462-1470. (SCI期刊)
    14. Dan-Kai Yang, Jie-Len Huang, Chia-Chun Chen, Hung-Ju Su, Jui-Chuang Wu* , “Enhancement of target-DNA hybridization efficiency by pre-hybridization on sequence-orientated micro-arrayed probes” , 2008 , Journal of the Chinese Institute of Chemical Engineers , vol.39 , p.187-193. (SCI期刊)
    15. Y.W. Chen-Yang, Y.K. Lee, Y.T. Chen, J.C. Wu , “High improvement in the properties of exfoliated PU/clay nanocomposites by the alternative swelling process” , 2007 , Polymer , vol.48 , p.2969-2979. (SCI期刊)
    16. Jui-Chuang Wu*, Shih-Yuan Lu* , “Selectivity for Patch-Distributed Reactive Spherical Surfaces” , 2007 , AIChE Journal , vol.53 , p.475-478. (SCI期刊)
    17. Jui-Chuang Wu*, Shih-Yuan Lu , “Patch-distribution effect on diffusion-limited process in dilute suspension of partially active spheres” , 2006 , JOURNAL OF CHEMICAL PHYSICS , vol.124 , p.024911-1-024911-6. (SCI期刊)

專利

    1. Yui Whei Chen-Yang; Jui-Chuang Wu; Yen Kuang Li; Yun-Chu Chen , “BIOCHIP ARRAYED WITH A THREE-DIMENSIONAL STRUCTURE AND METHOD FOR FORMING THE SAME” , 發明 , 2014 , 美國 , USA Patent 8,735,084 B2 (2014.5) .
    2. Yui Whei Chen-Yang; Jui-Chuang Wu; Yen Kuang Li; Huan-Ching Yang , “BIOCHIP WITH A THREE DIMENSIONAL MESOPOROUS LAYER” , 發明 , 2013 , 美國 , USA Patent 8,574,498 B2 (2013.11) .
    3. Yui Whei Chen-Yang; Jui-Chuang Wu; Yen Kuang Li; Huan-Ching Yan , “BIOCHIP WITH A THREE DIMENSIONAL MESOPOROUS LAYER AND METHOD FOR FORMING THE SAME,” , 發明 , 2013 , 美國 , USA Patent 8,394,323 B2 (2013.3) .
    4. 陳玉惠; 吳瑞璋; 李彥廣; 陳韻竹 , “具有三維立體結構之陣列式生物晶片及其形成方法” , 發明 , 2012 , 中華民國 台灣 , I 374266 (2012.10) .
    5. 陳玉惠;吳瑞璋;李彥廣;楊環菁 , “具有三維立體結構中孔洞材料層之生物晶片及其形成方法” , 2010 , 中華民國 台灣 , I 327990 (2010) .

研討會論文

    1. 盧昶竹; 林予梵; 黃亭慈; 吳瑞璋*; 黃郁慈* , “快速偵測廢水處理系統中厭氧氨氧化菌種之技術” , 2020 , 2020第四屆台灣碳材料學術研討會 , 2020 /11 /2 ~ 2020 /11 /3 , 中華民國 台灣 .
    2. Hsu-Chieh Cheng; Ting-Tzu Huang; Yu-Tzu Huang*; Jui-Chuang Wu* , “Rapid Detection of Total Anaerobic Ammonium Oxidizing(Anammox) Bacteria in Activated Sludge and Evaluation of Ammonia Removal Efficiency Using the Lateral-flow Immunochromatographic Assa” , 2020 , ICSS 2020 International Conference on Smart Sensors , 2020 /10 /19 ~ 2020 /10 /20 , 中華民國 台灣 .
    3. Chang-Zhu Lu; Yu-Fan Lin; Ting-Cih Huang; Jui-Chuang Wu; Yu-Tzu Huang , “Technology for rapid detection of anammox bacteria in wastewater treatment system” , 2020 , 台灣化學工程學會67週年年會暨科技部化學工程學門成果發表會 , 2020 /10 /23 ~ 2020 /10 /24 , 中華民國 台灣 .
    4. 鄭旭傑; 楊家誠; 吳瑞璋* , “Rapid Detection of Single Nucleotide Polymorphism(SNP) variation of Gene sequence HLA-A3101 Using Lateral-flow Immunochromatographic Assay” , 2019 , 台灣化學工程學會66週年年會暨科技部化學工程學門成果發表會 , 2019 /11 /8 ~ 2019 /11 /9 , 中華民國 台灣 .
    5. Jui-Chuang Wu*; Shih-En Jha; Hsun-Yu Huang; Guan-Ting Lin, , “Detection of Autoimmune-Disease Genes on Membrane-Based Lateral-Flow Strips” , 2019 , 4th International Conference on Recent Multidisciplinary Research (4th ICRMR-2019) , 2019 /6 /29 ~ 2019 /6 /30 , Hungary .
    6. Jui-Chuang Wu*; Shih-En Jha , “Rapid Detection of Multiple Gene Sequences on A Membrane-Based Lateral-Flow Strip” , 2019 , 23th International Conference on Engineering, Technology and Applied Science , 2019 /4 /18 ~ 2019 /4 /19 , Republic of Korea .
    7. 莊英煥; 魏瑜均; 吳瑞璋; 吳光哲 , “以磁珠及奈米金快速側向流免疫法感測前列腺癌生物指標誌物” , 2018 , 台灣化學工程學會65週年年會暨科技部化學工程學門成果發表會 , 2018 /11 /9 ~ 2018 /11 /10 , 中華民國 台灣 .
    8. Jui-Chuang Wu*, Yu-Shiun Huang , “Rapid Detection of Gene HLA-A3101 on Membrane Based Lateral-Flow Strips” , 2018 , 2018 9th International Conference on Food Engineering and Biotechnology (ICFEB 2018) , 2018 /3 /28 ~ 2018 /3 /30 , Japan .
    9. 吳瑞璋; 黃昱勛; 查士恩 , “以薄膜側向流免疫層析法對HLA-A3101基因序列之快速偵測 ” , 2017 , 2017台灣化學工程師年會 , 2017 /11 /17 ~ 2017 /11 /18 , 中華民國 台灣 .
    10. Jui-Chuang Wu; Guwan-Tin Lin , “Detection of Gene HLA-Cw1602 on Lateral-flow Strips” , 2017 , 2017 ACENS Asian Conference on Engineering and Natural Sciences , 2017 /1 /19 ~ 2017 /1 /21 , Japan .
    11. Jui-Chuang Wu; Chung-Kun Ho; Hsing-Wen Low; Guang-Jer Wu , “An early diagnostic biomarker for the malignant progression of prostate cancer.” , 2016 , IMCS2016 The 16th International Meeting on Chemical Sensors , 2016 /7 /10 ~ 2016 /7 /13 , Republic of Korea .
    12. Jui-Chuang Wu*; Yue-Je Jung , “Detection of Gene HLA-B5801 on A Lateral-Flow Membrane” , 2016 , 6th International Scientific conference on Applied Sciences and Engineering , 2016 /1 /26 ~ 2016 /1 /27 , Republic of Singapore .
    13. 何仲;吳瑞璋;吳光哲;陳玉惠 , “惡性轉移前列腺癌生物標誌METCAM/MUC18早期之診斷” , 2015 , 2015台灣化學工程師年會 , 2015 /11 /5 ~ 2015 /11 /7 , 中華民國 台灣 .
    14. Jui-Chuang Wu; Ja-Wei Fu , “Detection of Biological Samples on Membrane-Based Lateral-Flow ” , 2015 , 3D and Materials Research , 2015 /6 /15 ~ 2015 /6 /19 , Republic of Korea .
    15. 鍾岳哲;傅佳瑋;陳志宏;吳瑞璋 , “施加直流電場於側向流薄膜試條以增強去氧核糖核酸之偵測” , 2014 , 2014台灣化學工程學會年會 , 2014 /11 /5 ~ 2014 /11 /7 , 中華民國 台灣 .
    16. Jui-Chuang Wu*; Chih-Hung Chen; and Huang-Chin Yang , “Electric Field-Enhanced One-Step Visual Detection of PCR Products on A Membrane-Based Lateral Flow” , 2013 , Life Science and Biological Engineering , 2013 /11 /6 ~ 2013 /11 /8 , Japan .
    17. 傅佳瑋; 吳瑞璋; 陳玉惠 , “具環氧官能基之中孔洞氣凝膠應用於快速側向流免疫抗體偵測” , 2013 , 2013台灣化學工程師年會 , 2013 /11 /22 ~ 2013 /11 /23 , 中華民國 台灣 .
    18. 吳瑞璋; 鄭丹蘋; 鄭雅云; 陳志宏 , “標定奈米金之合酸滾動循環擴增技術應用於側向流免疫層析法 對禽流感DNA之偵測” , 2013 , 化學感測器科技研討會 , 2013 /6 /1 ~ 2013 /6 /1 , 中華民國 台灣 .
    19. Jui-Chuang Wu; Yai-Hsin Hsu; Dan-Ping Cheng; Ya-Yuen Cheng , “Detection of Deoxyribonucleic Acids on A Membrane Strip” , 2013 , The 5th International Conference on Bioinformatics and Biomedical Technology, May 16 Macau , 2013 /3 /16 ~ 2013 /3 /17 , Macau .
    20. Jui-Chuang Wu; Dan-Kai Yang; Yane-Shu Lin; Jun-Yi Chen , “Investigation of Hybridization Efficiency of A Sequence-Orientated Coaxial DNA Probe Microarryed on Biohips Using Atomic Force ” , 2012 , The 2nd International Conference of Engineering and Technology Innovation , 2012 /11 /2 ~ 2012 /11 /6 , 中華民國 台灣 .
    21. 李湘儒、吳瑞璋* , “The Peel Test and Water-Vapor Permeability Measurement of A PVA Coating Film on A Nano-Porous PTFE Membrane” , 2012 , 2012臺灣化學工程師年會 , 2012 /11 /23 ~ 2012 /11 /24 , 中華民國 台灣 .
    22. Jui-Chuang Wu*; Huang-Chin Yang; and Ya-Ju Chang , “The Membrane-Based Lateral Flow Detection of Avian Influenza” , 2011 , 2011 International Membrane Conference in Taiwan , 2011 /5 /26 ~ 2011 /5 /26 .
    23. Jiun Yi Chen; Sun-Hua Pao; Jie-Len Huang; Chia-Chun Chen; Hung-Ju Su; Jui-Chuang Wu , “Investigation of DNA Hybridization Efficiency by Orientated Co-Axial Probes on DNA-Arrayed Biochips Using Atomic Force Microscope” , 2010 , The 13th Asia Pacific Confederation of Chemical Engineering Congress , 2010 /10 /5 ~ 2010 /10 /8 .
    24. Yen Kuang Li; Den-Kai Yang; Yun-Chu Chen; Hung-Ju Su; Jui-Chuang Wu*; Yui Whei Chen-Yang* , “An Application of Nano-porous Aerogel on A Gene Biosensor” , 2010 , 2010 International Conference On Nanoscience and Nanotechnology , 2010 /2 /23 ~ 2010 /2 /25 .
    25. Yen Kuang Li; Kai-Jen Jiang; Yun-Chu Chen; Jui-Chuang Wu*; Yui Whei Chen-Yang* , “A nano-porous aerogel biochip for molecular recognition of nucleotide acids” , 2009 , 2009 Medical Physics and Biomedical Engineering , 2009 /9 /7 ~ 2009 /9 /12 .
    26. Yen Kuang Li; Den-Kai Yang; Yun-Chu Chen; Hung-Ju Su; Jui-Chuang Wu; Yui Whei Chen-Yang , “A Nanoporous Aerogel Biochip for Recognition of Immune Antigens” , 2009 , NanoToday 2009 , 2009 /8 /2 ~ 2009 /8 /5 .
    27. 許曜薪, 吳瑞璋 , “利用核酸滾動循環擴增技術於側向流免疫層析膜上之訊號放大” , 2009 , 第十四屆生化工程研討會 , 2009 /6 /5 ~ 2009 /6 /6 .
    28. 姜凱仁, 蘇弘儒, 吳瑞璋 , “利用微陣列基因探針進行預雜交以增強DNA雜交效率” , 2009 , 第十四屆生化工程研討會 , 2009 /6 /5 ~ 2009 /6 /6 .
    29. Jui-Chuang Wu; Vanilyn Limcuando , “A Study on the Interaction of Streptomyces Coelicolor Proteins (TpgC and TapC) Using a SPR Sensor” , 2009 , 1st Regional Conference on Chemical Engineering , 2009 /1 /22 ~ 2009 /1 /23 .
    30. Jui-Chuang Wu; Hwan-Gin Yang , “Membrane Based Later-Flow Detection of Avian Flu” , 2008 , 100th AIChE Annuanl Meeting , 2008 /11 /16 ~ 2008 /11 /21 .
    31. Jui-Chuang Wu , “Preparation of Three -Dimensional Aerogel Protein Array” , 2007 , 234th ACS National Meeting , 2008 /8 /19 ~ 2008 /8 /23 .
    32. 葉庭秀, 吳凱智, 吳瑞璋 , “Fluorescent-Signal Amplification and Optimization of Cytokine Microarray Using Rolling-Circle Amplification Technique” , 2007 , 第十三屆化學感測器研討會 , 2007 /5 /26 ~ 2007 /5 /26 .
    33. 吳凱智, 葉庭秀, 吳瑞璋 , “Optimization of An Immunochromatographic Assembly and Rapid Detection to Streptavidin Protein ” , 2007 , 第十三屆化學感測器研討會 , 2007 /5 /26 ~ 2007 /5 /26 .
    34. Jui-Chuang Wu, Dan-Kai Yang, Jie-Len Huang, Chia-Chun Chen, and Hung-Ju Su , “The Effect of Pre-Hybridizing DNA on Hybridization Efficiency of Subsequent Target on Microarrayed Biochips” , 2007 , 2007 Advances in Microarray Technology , 2007 /5 /15 ~ 2007 /5 /16 .
    35. Jui-Chuang Wu, Hwang-Jin Yung, Yan-Gwan Li,Yui-Whei Chen , “Preparation of Three-Dimensional Aerogel Biochips” , 2006 , The 10th Annual European Conference on Micro and Nanoscale Technologies for the Biosciences , 2006 /11 /14 ~ 2006 /11 /16 .
    36. Jui-Chuang Wu, Shih-Yuan Lu , “Effect of Patch Distribution on Reaction Selectivity” , 2006 , 2006 Symposium on Transport Phenomena and Applications , 2006 /9 /29 ~ 2006 /9 /29 .
    37. Jui-Chuang Wu and Ya-Tin Lee , “Preparation of ImmnuoDetection Chips of TpgC Protein” , 2006 , 12th Chemical Sensior Conference , 2006 /5 /27 ~ 2006 /5 /27 .
    38. Jui-Chuang Wu, Dan-Kai Yang, Jie-Len Huang, Chia-Chun Chen, and Hung-Ju Su , “The Effect of Molecular Steric Hindrance on Microarrayed DNA Hybridization Efficiency” , 2006 , The 2nd International Meeting on Microsensors and Microsystems , 2006 /1 /15 ~ 2006 /1 /18 .
    39. Yun-Gaun Li,Yu-Huey Chen, Haun-Gin Yung, Jui-Chuang Wu , “Preparation of Aerogel DNA Biochips” , 2006 , The 29th Polymer Conference , 2006 /1 /13 ~ 2006 /1 /14 .
    40. J. C. Wu, S. Y. Lu , “A separation index correlating patch distribution with diffusion-limited rate constants” , 2005 , 2005 Symposium on Transport Phenomena and Applications , 2005 /11 /11 ~ 2005 /11 /11 .
    41. Jui-Chuang Wu, et al. , “Development of A Silanization CVD Process for an Ultra-Hight Throughtput SNP Genotyping Platform” , 2001 , 2001 AIChE Annual Conference , 2001 /11 /6 ~ 2001 /11 /10 .